This article provides an introduction to this special issue of ArtMatters presenting essays developed from the online international symposium New Technical Research on Rembrandt: Paintings, Drawings, Prints organised by the Städel Museum, Frankfurt, in January 2022. Focusing on paintings, seven papers report on recent technical investigations of works by Rembrandt and his studio in the collections of the Städel Museum; the Agnes Etherington Art Centre, Queen’s University, Kingston, Canada; the Ashmolean Museum, Oxford; the Gemäldegalerie Alte Meister, Hessen Kassel Heritage; the Gemäldegalerie, Staatliche Museen zu Berlin; the Hessisches Landesmuseum, Darmstadt; the Mauritshuis, The Hague; and the National Gallery of Art, Washington, DC. Co-authored by art historians, conservators and scientists, these essays explore how current technologies and methods can shed new light on Rembrandt’s painting techniques and workshop practice while pointing the way to future research. This introduction summarises key themes and discoveries that tie these studies together.